Trim5 alpha (3B11) Antibody

Cat no: 252615

Supplier: ABBIOTEC

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Description
Additional Information

TRIM5-alpha (Tripartite motif-containing protein 5) is a protein that is found in the cells of many mammals and fends off various retrovirus infections. It protects monkeys from infection with HIV-1 and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be e, Xenopus/Amphibian,pressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.

Catalogue number:	252615
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	Q9C035
Antigen:	Purified recombinant fragment of human trim5 alpha e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3B11H2
Additional info:	Tripartite motif-containing protein 5; RING finger protein 88; RNF88; TRIM5