Home  >  Products  >  Trinactin (Antibiotic AKD-1D, Antibiotic S 3466B)

Trinactin (Antibiotic AKD-1D, Antibiotic S 3466B)

Cat no: T8470


Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Trinactin is a member of the macrotetrolide complex produced by a range of Streptomyces sp. Early literature reported that trinactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Trinactin inhibited T-cell proliferation induced by IL-2 and cytokine production at nonomolar levels for IL-2, IL-4, IL-5 and interferon-gamma. Trinactin has not previously been available for intensive investigation. Purity: >95% by HPLC Solubility: Soluble in ethyl acetate or DMSO, moderately in soluble ethanol or methanol. Related to: Monactin, Dinactin
Catalogue number: T8470
Size: 1mg
Purity: >95% by HPLC
Alternative names: Antibiotic AKD-1D, Antibiotic S 3466B
References: 1. Effects of cyclosporin A and dinactin on T-cell proliferation, interleukin-5 production, and murine pulmonary inflammation. Umland S.P. et al. Am. J. Respir. Cell Mol. Biol. 1999, 20, 481. 2. Immunosuppressive effects of polynactins (tetranactin, trinactin and dinactin) on experimental autoimmune uveoretinitis in rats. Tanouchi Y. et al. Jpn. J. Ophthalmol. 1987, 31, 218. 3. Antibiotics as tools for metabolic studies. VI. Damped oscillatory swelling of mitochondria induced by nonactin, monactin, dinactin, and trinactin. Graven S.N. et al. Biochemistry 1966, 5, 1735.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*

Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave