Home  >  Products  >  TRIP6 (Thyroid Receptor-interacting Protein 6, TR-interacting Protein 6, TRIP-6, Opa-interacting Protein 1, OIP-1, Zyxin-related Protein 1, ZRP-1, OIP1)
TRIP6 (Thyroid Receptor-interacting Protein 6, TR-interacting Protein 6, TRIP-6, Opa-interacting Protein 1, OIP-1, Zyxin-related Protein 1, ZRP-1, OIP1)

TRIP6 (Thyroid Receptor-interacting Protein 6, TR-interacting Protein 6, TRIP-6, Opa-interacting Protein 1, OIP-1, Zyxin-related Protein 1, ZRP-1, OIP1)

Cat no: T8494-01B

Supplier: United States Biological
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This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Western Blot: 1-3ug/ml, observed in lysates of cell line K562 on ~50kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8494-01B
Reactivities: Human, Bovine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Shanmugarajan S, Kawanabe N, Koide M, Tsuruga E, Arroyo JE, Key LL, Reddy SV, IL-12 stimulates the osteoclast inhibitory peptide-1 (OIP-1/hSca) gene expression in CD4+ T cells. Journal of cellular biochemistry 2009 May 107(1):104-11.
Additional info: Recognizes human TRIP6. Species sequence homology: Bovine.

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