Trop-2 Antibody

Cat no: 251611

Supplier: ABBIOTEC

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Description
Additional Information

TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), gp50 and T16, is a type I cell surface glycoprotein that is highly e, Xenopus/Amphibian,pressed on human carcinomas. (Trop-2) is necessary for tumorigenesis and invasiveness of colon cancer cells, as both are inhibited when Trop-2 e, Xenopus/Amphibian,pression is suppressed by RNA interference. Defects in trop-2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.

Catalogue number:	251611
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P09758
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human trop-2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Trop-2; Tumor-associated calcium signal transducer 2; Pancreatic carcinoma marker protein GA733-1; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; TACSTD2; GA733-1; M1S1; TROP2