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Trop-2 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251611

Trop-2 Antibody

TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), gp50 and T16, is a type I cell surface glycoprotein that is highly e, Xenopus/Amphibian,pressed on human carcinomas. (Trop-2) is necessary for tumorigenesis and invasiveness of colon cancer cells, as both are inhibited when Trop-2 e, Xenopus/Amphibian,pression is suppressed by RNA interference. Defects in trop-2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.

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SPECIFICATIONS

Catalog Number

251611

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human trop-2.

Isotype

Rabbit Ig

Accession

P09758

Additional Info

Trop-2; Tumor-associated calcium signal transducer 2; Pancreatic carcinoma marker protein GA733-1; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; TACSTD2; GA733-1; M1S1; TROP2

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