Tropomyosin (36/39 kD) (CMH3, TMSA, CMD1Y, C15orf13, HTM-alpha, Alpha-tropomyosin, Tropomyosin-1)

The tropomyosins are a family of actin filament binding proteins. These proteins were first isolated from skeletal muscle, but later identified in many nonmuscle tissues. Tropomyosins are ubiquitous proteins of 35 to 45 kD associated with the actin filaments of myofibrils and stress fibers. Vertebrates have at least 4 different tropomyosin genes; in humans, they are named TPM1, TPM2, TPM3, and TPM4. Tropomyosins expressed as different isoforms in muscle and non-muscle cells.\n\nUniProt Number:\nHuman(P09493), Mouse(P58771), Rat(P04692)\n\nGene ID:\nTPM1\n\nApplications:\nSuitable for use in Western Blot.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Handling:\nStore at -20?C for one year. After reconstitution, store at 4?C for one month. Can also be aliquoted and stored frozen at -20?C for long term.\nAvoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

145321

Size

100ug

Applications

WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Ch/Bird

Form

Ascites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

P Type

Mab

Isotype

IgG1

References

1. Lees-Miller, J. P.; Helfman, D. M. : The molecular basis for tropomyosin isoform diversity. BioEssays 13: 429-437, 1991.\n2. Gariboldi, M.; Manenti, G.; Dragani, T. A.; Pierotti, M. A. : Chromosome mapping of nine tropomyosin-related sequences in mice. Mammalian Genome 6: 273-277, 1995.\n\n

Additional Info

Recognizes human, mouse, rat and chicken Tropomyosin (36/39 kDa). No crossreactivity with other proteins.