Home  >  Products  >  Troponin I, Cardiac (Cardiac Troponin I, Troponin I Cardiac Muscle, cTnI, TNNC1, CMD1FF, CMD2A, CMH7, MGC116817, RCM1, TNNI3)
Troponin I, Cardiac (Cardiac Troponin I, Troponin I Cardiac Muscle, cTnI, TNNC1, CMD1FF, CMD2A, CMH7, MGC116817, RCM1, TNNI3)

Troponin I, Cardiac (Cardiac Troponin I, Troponin I Cardiac Muscle, cTnI, TNNC1, CMD1FF, CMD2A, CMH7, MGC116817, RCM1, TNNI3)

Cat no: T8665-15F

Supplier: United States Biological
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Troponin I is a 24kD subunit of Troponin, a protein found on muscle tissue responsible for muscle contraction. When calcium binds to Troponin C, a conformational change moves Troponin I and tropomyosin out of the way of the myosin binding sites on the actin filaments in muscles. This allows cross-bridging to occur and the muscle to contract. Levels of cTnI in serum are commonly used as a marker for cardiac cell damage and death. Applications: Suitable for use in ELISA, Immunoprecipitation and Western Blot. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8665-15F
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Immunoprecipitation, Western Blot
Size: 200ug
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
Alternative names: Troponin I Type 3 (Cardiac)
Additional info: Regognizes an epitope between aa 87- 91 of human cardiac Troponin I (cTnI). Does not cross react with skeletal TnI. Species crossreactivity: Reacts weakly with: bovine, goat, rabbit, feline, porcine and canine. Does not react with rat, fish or mouse.

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