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Products Troponin I, Cardiac, Human (cTnI, CMH7, Familial Hypertrophic Cardiomyopathy 7, MGC116817, Troponin-I, Troponin I Cardiac Muscle, TNNC 1, TNNC1, Troponin I Type 3 Cardiac, TNNI3)
| Catalogue number: | T8665-14U |
| Reactivities: | Human, Rat, Bovine, Canine, Feline, Goat, Porcine |
| Hosts: | Mouse |
| Applications: | ELISA, Western Blot |
| Size: | 200ug |
| Form: | Supplied as a liquid in PBS, pH 7.2. |
| P type: | Mab |
| Isotype: | IgG1 |
| Purity: | Purified by Protein A affinity chromatography. |
| References: | Marston SB & Redwood CS Modulation of thin filament activation by breakdown or isoform switching of thin filament proteins: physiological and pathological implications. Circ Res 93:1170-8 (2003). Sarko J & Pollack CV Cardiac troponins. J Emerg Med 23:57-65 (2002). Gomes AV et al. The role of troponins in muscle contraction. IUBMB Life 54:323-33 (2002). Onuoha GN et al. Skeletal troponin-I release in orthopedic and soft tissue injuries. J Orthop Sci 6:11-5 (2001). Labugger R et al. Extensive troponin I and T modification detected in serum from patients with acute myocardial infarction. Circulation 102:1221-6 (2000). Reiffert SU et al. Stepwise subunit interaction changes by mono- and bisphosphorylation of cardiac troponin I. Biochemistry 37:13516-25 (1998). |
| Additional info: | This antibody is reacting with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponin components (In the presence of 5 mM EDTA). It is not affected by heparin, phosphorylation, oxidation and troponin complex formation.This antibody does not crossreact with skeletal muscle troponin I. Species Crossreactivity: Crossreacts with Rat, bovine, Cat, canine, Goat, porcine and Human. Does not crossreact with Fish or Rabbit. |
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