Home  >  Products  >  Troponin T, Cardiac (Troponin T Cardiac Muscle, TnTC, Troponin T Type 2 (Cardiac), Troponin T2, TNNT2, Cardiac Muscle Troponin T, cTnT, CMD1D, CMH2, MGC3889)
Troponin T, Cardiac (Troponin T Cardiac Muscle, TnTC, Troponin T Type 2 (Cardiac), Troponin T2, TNNT2, Cardiac Muscle Troponin T, cTnT, CMD1D, CMH2, MGC3889)

Troponin T, Cardiac (Troponin T Cardiac Muscle, TnTC, Troponin T Type 2 (Cardiac), Troponin T2, TNNT2, Cardiac Muscle Troponin T, cTnT, CMD1D, CMH2, MGC3889)

Cat no: T8665-23N

Supplier: United States Biological
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Troponin T, also known as TNNT2, is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with restrictive and dilated cardiomyopathy. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8665-23N
Reactivities: Human, Mouse, Rat, Bovine, Canine, Feline, Goat, Porcine, Rabbit
Hosts: Mouse
Applications: ELISA
Size: 200ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
P type: Mab
Isotype: IgG2b
Purity: Purified by Protein A affinity chromatography.
References: 1. Sarko J & Pollack CV Cardiac troponins. J Emerg Med 23:57-65 (2002). 2. Gomes AV et al. IUBMB Life 54:323-33 (2002). 3. Hamm CW Thromb Res 103 Suppl 1:S63-9 (2001). 4. Labugger R et al. Circulation 102:1221-6 (2000). 5. Wu AH et al. Clin Chem 44:1198-208 (1998). 6. Katrukha AG et al. Clin Chem 43:1379-85 (1997).
Additional info: Recognizes human Troponin T at ~35.4kD. Species Crossreactivity: mouse, rat, bovine, feline, canine, goat, porcine and rabbit. Does not crossreact with Fish. Does not crossreact with skeletal TnT.

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