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TRPC3 (CT) (Transient Receptor Potential Cation Channel, Subfamily C, Member 3, HTRP-3, HTRP3, TRP3)

TRPC3 (CT) (Transient Receptor Potential Cation Channel, Subfamily C, Member 3, HTRP-3, HTRP3, TRP3)

Cat no: T8666-14B

Supplier: United States Biological
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TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels. Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: T8666-14B
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS. No preservative added.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Contell, C., et al., (2002), "A unified nomenclature for the superfamily of TRP cation channels", Mol. Cell., 9: 229-231. 2. Trebak, M., et al., (2003), "The TRPC3/6/7 subfamily of cation channels", Cell Calcium, 33: 451-461. 3. Zitt, C., et al., (1997), "Expression of TRPC3 in Chinese hamster ovary cells results in calcium-activated cation currents not related to store depletion", J. Cell. Bio., 138(6):, 1333-1341. 4. Dietrich, A., et al., (2005), "The diacylglycerol-sensitive TRPC3/6/7 subfamily of cation channels: functional characterization and physiological relevance", Pflugers Arch., 451: 72-80.
Additional info: Recognizes S the C-terminus of human TRPC3. Species Crossreactivity: mouse, rat.

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