Home  >  Products  >  TRPC6, NT (Transient Receptor Potential Cation Channel Subfamily C Member 6, TRP6, TRPC 6, TRPC6, TRRP6, bZ1P14.9, FLJ11098, FLJ14863, FSGS2, HGNC:12338, MTRP6, Short Transient Receptor Potential Channel 6)(Calcium entry channel)
TRPC6, NT (Transient Receptor Potential Cation Channel Subfamily C Member 6, TRP6, TRPC 6, TRPC6, TRRP6, bZ1P14.9, FLJ11098, FLJ14863, FSGS2, HGNC:12338, MTRP6, Short Transient Receptor Potential Channel 6)(Calcium entry channel)

TRPC6, NT (Transient Receptor Potential Cation Channel Subfamily C Member 6, TRP6, TRPC 6, TRPC6, TRRP6, bZ1P14.9, FLJ11098, FLJ14863, FSGS2, HGNC:12338, MTRP6, Short Transient Receptor Potential Channel 6)(Calcium entry channel)

Cat no: T8666-30F

Supplier: United States Biological
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When expressed in transfected cells, TRPC6 acts as a non-selective store-independent receptor-activated cation channel. It is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation. There is increasing evidence that TRPC6 encodes endogenous DAG-activated receptor-operated cation channels in vivo. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: T8666-30F
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.02% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Contell, C., et al., (2002), "A unified nomenclature for the superfamily of TRP cation channels", Mol. Cell., 9: 229-231.2. Dietrich, A., et al., (2005), "The diacylglycerol-sensitive TRPC3/6/7 subfamily of cation channels: functional characterization and physiological relevance", Pflugers Arch., 451: 72-80.3. Trebak, M., et al., (2003), "The TRPC3/6/7 subfamily of cation channels", Cell Calcium, 33: 451-461.
Additional info: Recognizes the N-terminus of human TRPC6. Species Crossreactivity: mouse.

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