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TRPC6 (Short Transient Receptor Potential Channel 6, TrpC6, Transient Receptor Protein 6, TRP-6, TRP6)

TRPC6 (Short Transient Receptor Potential Channel 6, TrpC6, Transient Receptor Protein 6, TRP-6, TRP6)

Cat no: T8666-30K

Supplier: United States Biological
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The TRPM6 (Transient Receptor Protein-PhosphoLipase C-Interacting Kinase) protein is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. It is also upregulated in certain forms of cancer and could play a role in diabetes. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Western Blot: 0.03-0.1ug/ml, observed in human placenta lysates on ~110kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8666-30K
Reactivities: Human, Bovine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Foller M, Kasinathan RS, Koka S, Lang C, Shumilina E, Birnbaumer L, Lang F, Huber SM. TRPC6 contributes to the Ca(2+) leak of human erythrocytes. Cell Physiol Biochem. 2008;21(1-3):183-92. Epub 2008 Jan 16.
Additional info: Recognizes human TRPC6. Species sequence homology: Bovine.

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