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TRPC6 (Short Transient Receptor Potential Channel 6, TrpC6, Transient Receptor Protein 6, TRP-6, TRP6)

TRPC6 (Short Transient Receptor Potential Channel 6, TrpC6, Transient Receptor Protein 6, TRP-6, TRP6)

Cat no: T8666-30L

Supplier: United States Biological
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The TRPM6 (Transient Receptor Protein-PhosphoLipase C-Interacting Kinase) protein is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. It is also upregulated in certain forms of cancer and could play a role in diabetes. Applications: Suitable for use in Flow Cytometry and ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8666-30L
Reactivities: Human, Mouse, Bovine, Canine, Porcine
Hosts: Goat
Applications: ELISA, Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Winn MP, Conlon PJ, Lynn KL, Farrington MK, Creazzo T, Hawkins AF, Daskalakis N, Kwan SY, Ebersviller S, Burchette JL, Pericak-Vance MA, Howell DN, Vance JM, Rosenberg PB. A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science. 2005 Jun 17;308(5729):1801-4. Epub 2005 May 5.
Additional info: Recognizes mouse TRPC6. Species sequence homology: Human, bovine, canine and porcine.

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