Tubulin beta-3 Antibody

Cat no: 253232

Supplier: ABBIOTEC

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Description
Additional Information

Tubulin is the major constituent of microtubules, e, Xenopus/Amphibian,isting as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost e, Xenopus/Amphibian,clusively in neuronal processes of adult tissues and is therefore an e, Xenopus/Amphibian,cellent marker for neurons. Neuron specific,Porcineosttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated, suggesting that they modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly e, Xenopus/Amphibian,pressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.

Catalogue number:	253232
Reactivities:	Human, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	Q4QRB4
Antigen:	KLH-conjugated peptide encompassing a sequence within rat tubulin, beta III.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	AA10
Additional info:	Tubulin beta-3 chain; Neuron-specific class III beta-tubulin; Tubb3