Tubulin, beta 3 (Tubulin beta III, Tubulin beta 3 Chain, TUBB 3, TUBB3, Neuron Specific beta III Tubulin, beta-4, MC1R, Tubulin beta 4, TUBB 4, TUBB4)

The beta-tubulin III protein belongs to the tubulin superfamily and is abundant in the brain, where it is expressed almost exclusively in neurons after differentiation. There are significant post-translational modifications made to beta-tubulin III with numerous isoforms present during early post-natal neural development. Altered patterns of expression are noted in brain tumors such as medulloblastomas.\n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:500-1:1000\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nNormal human brain lysate\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

T9155-01U

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, 0.02% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Piper, D.R, Mujtaba, T., Keyoung, H., Roy, N.S., Goldman, S.A., Rao, M.S. and Lucero, M.T. Identification and characterization of neuronal precursors and their progeny from human fetal tissue. J Neurosci Res. 2001 Nov 1;66(3):356-68. 2. Robertson, M.J., Gip, P. and Schaffer, D.V. Neural stem cell engineering: directed differentiation of adult and embryonic stem cells into neurons. Front Biosci. 2008 Jan 1;13:21-50. 3. Encinas, J.M. and Enikolopov, G. Identifying and quantitating neural stem and progenitor cells in the adult brain. Methods Cell Biol. 2008;85:243-72.

Additional Info

Recognizes human Tubulin, beta 3. Species Crossreactivity: mouse and rat.