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Tubulin beta (Beta-tubulin, Tubulin beta Chain)

Tubulin beta (Beta-tubulin, Tubulin beta Chain)

Cat no: T9154-05G1

Supplier: United States Biological
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Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55kD subunits: alpha and beta. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.1-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T9154-05G1
Reactivities: Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Non-Human Primate, Xenopus/Amphibian
Hosts: Rabbit
Applications: Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
References: 1. Yeh,T.S., Hsieh,R.H., Shen,S.C., Wang,S.H., Tseng,M.J., Shih,C.M. and Lin,J.J. Nuclear betaII-tubulin associates with the activated notch receptor to modulate notch signaling. Cancer Res. 64 (22), 8334-8340 (2004). 2. Takahashi,M., Shiraishi,H., Ishibashi,Y., Blade,K.L., McDermott,P.J., Menick,D.R., Kuppuswamy,D. and Cooper,G. IV. Phenotypic consequences of beta1-tubulin expression and MAP4 decoration of microtubules in adult cardiocytes. Am. J. Physiol. Heart Circ. Physiol. 285 (5), H2072-H2083 (2003).
Additional info: Recognizes human beta Tubulin. Species Crossreactivity: bovine, chicken, canine, monkey, mouse, rat, xenopus.

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