Home  >  Products  >  Tumor Endothelial Marker 5 (TEM5, FLJ14390, G Protein-coupled Receptor 124, G-protein Coupled Receptor 124, GPR124, KIAA1531)
Tumor Endothelial Marker 5 (TEM5, FLJ14390, G Protein-coupled Receptor 124, G-protein Coupled Receptor 124, GPR124, KIAA1531)

Tumor Endothelial Marker 5 (TEM5, FLJ14390, G Protein-coupled Receptor 124, G-protein Coupled Receptor 124, GPR124, KIAA1531)

Cat no: T9160-50E

Supplier: United States Biological
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Tumor endothelial marker 5 is an Orphan-U GPCR with an unknown ligand. Tumor Endothelial Marker 5, like GPR125, has a leucine rich repeat (LRR), an immunoglobulin (Ig) domain, and a hormone-binding domain (HBD). The Ig domain shows similarities to motilin and titin, while the LRR domain shows similarities to LRIG1 and SLIT1-2. TEM5 expression has been documented in endothelial cells of tumors, including colon, brain, liver. Expression is restricted largely to endothelial cells (St Croix et al. 2000). Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 4ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Colon carcinoma, Neoplastic cells Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T9160-50E
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: DKFZp434C211, DKFZp434J0911
Additional info: Recognizes human GPR124.

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