Home  >  Products  >  Tumor Necrosis Factor alpha (TNF alpha, TNF-alpha, TNF a, TNFa, TNF-a, Cachectin, Differentiation Inducing Factor, DIF, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF Superfamily Member 2, TNFSF2)
Tumor Necrosis Factor alpha (TNF alpha, TNF-alpha, TNF a, TNFa, TNF-a, Cachectin, Differentiation Inducing Factor, DIF, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF Superfamily Member 2, TNFSF2)

Tumor Necrosis Factor alpha (TNF alpha, TNF-alpha, TNF a, TNFa, TNF-a, Cachectin, Differentiation Inducing Factor, DIF, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF Superfamily Member 2, TNFSF2)

Cat no: T9160-03P

Supplier: United States Biological
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Tumor Necrosis Factor alpha (TNF-alpha) is a cytokine which has diverse immunomodulatory, anti-tumor and toxic effects. TNF-alpha has been detected in diverse inflammatory status and appears to be a critical mediator in the lethality of septic shock. Furthermore, TNF-alpha has also been found in inflammatory foci such as synovial effusions in rheumatoid arthritis, systemic circulation in septic shock, parasitemia and rejection of renal transplants. The antibody shows neutralizing activity. Applications: Suitable for use in Flow Cytometry, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:10 Western Blot: 1:10 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T9160-03P
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in 0.02% sodium azide, 0.1% BSA.
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: APC1, Macrophage Cytotoxic Factor, MCF, Necrosin, TNF Macrophage-derived, TNF Monocyte-derived, Tumor Necrosis Factor Precursor
References: 1. Gerspach, J et al; Detection of membrane-bound Tumor Necrosis Factor (TNF): an analysis of TNF-specific reagents. Microsc Res Tech 2000, 50: 243
Additional info: Recognizes solube (17kD), membrane (26kD), and receptor-bound human TNF-alpha. Inhibits activity of soluble and membrane TNF-alpha.

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