Home  >  Products  >  Tumor Necrosis Factor alpha (TNF alpha, TNF-alpha, TNF a, TNFa, TNF-a, Cachectin, Differentiation Inducing Factor, DIF, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF Superfamily Member 2, TNFSF2)

Tumor Necrosis Factor alpha (TNF alpha, TNF-alpha, TNF a, TNFa, TNF-a, Cachectin, Differentiation Inducing Factor, DIF, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF Superfamily Member 2, TNFSF2)

Cat no: T9160-03Q


Supplier: United States Biological
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Tumor Necrosis Factor alpha (TNF-alpha) is a cytokine which has diverse immunomodulatory, anti-tumor and toxic effects. TNF-alpha has been detected in diverse inflammatory status and appears to be a critical mediator in the lethality of septic shock. Furthermore, TNF-alpha has also been found in inflammatory foci such as synovial effusions in rheumatoid arthritis, systemic circulation in septic shock, parasitemia and rejection of renal transplants. Applications: Suitable for use ELISA, Western Blot and Neutralization. Other applications not tested. Recommended Dilutions: Western Blot: 1:20 Neutralization: Inhibits ~50ug TNFa per ml. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T9160-03Q
Reactivities: Human, Non-Human Primate
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 500ul
Form: Supplied as a liquid, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Serum
Alternative names: APC1, Macrophage Cytotoxic Factor, MCF, Necrosin, TNF Macrophage-derived, TNF Monocyte-derived, Tumor Necrosis Factor Precursor
Additional info: Recognizes natural and recombinant human Tumor Necrosis Factor alpha. Inhibits the biological activity of natural and recombinant human Tumor Necrosis Factor alpha as determined with L929 and WEHI cells in a cytotoxicity assay. Does not crossreact with human lymphotoxin. Species Crossreactivity: Cynomolgus monkey, and Rhesus monkey

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