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Tumor Necrosis Factor beta, aa35-205, Recombinant, Human (TNF-beta, TNFb, Lymphotoxin-alpha, LT-alpha, LTA, Tumor Necrosis Factor Ligand Superfamily Member 1, TNFSF1)

Cat no: T9160-44H

Tumor Necrosis Factor beta, aa35-205, Recombinant, Human (TNF-beta, TNFb, Lymphotoxin-alpha, LT-alpha, LTA, Tumor Necrosis Factor Ligand Superfamily Member 1, TNFSF1)

TNF beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Recombinant TNF beta protein was expressed in E. coli.\n\nSource: \nRecombinant corresponding to aa35-205 of human TNF-beta/LTA 6x His tagged expressed in E. coli.\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MLPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANT DRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQK MVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL\nSPSTVFFGAF AL\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

T9160-44H

Size

50ug

Applications

WB

Form

Supplied as a liquid in 20mM Tris HCl, pH 8.0, 0.1M NaCl, 1mM DTT, 30% glycerol.

Purity

~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques.

References

1. Messer G, et al. (1991) J Exp Med. 173(1):209-19 2. Banner DW, et al. (1993) Cell. 73(3):431-45.\n

Alternative Names

Lymphotoxin alpha (TNF Superfamily, Member 1)

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