Tumor Protein D52-Like 1, Recombinant, Human (TPD52L1, hD53, hD53L1)

TPD52L1 (hD53, hD53L1) is a member of D52 gene family and overexpressed in human breast carcinoma. This protein contains coiled-coil motif, which is responsible for homo- and heteromeric interaction, and may be a regulator of cell proliferation and calcium-mediated signal transduction.\n\nDescription: \nRecombinant Human TPD52L1 His-Tag fusion proein produced in E.Coli is a single,non-glycosylated polypeptide chain containing amino acids 151 and having a molecular mass of 16.8kD.\n\nSequence: \nMGSSHHHHHH SSGLVPRGSH MEAQAQGLLE TEPLQGTDED AVASADFSSM LSEEEKEELK AELVQLEDEI TTLRQVLSAK ERHLVEIKQK LGMNLMNELK QNFSKSWHDM QTTTAYKKTH ETLSHAGQKA TAAFSNVGTA ISKKFGDMRR K\n\nStability: \nStore at 4 degrees C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degrees C for longer periods of time. Please avoid freeze-thaw cycles.

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SPECIFICATIONS

Catalog Number

T9164-50

Size

10ug

Form

Supplied as a liquid in PBS, pH 7.4.

Purity

(same/more than) 90% as determined by: \n(a) Analysis by RP-HPLC. \n(b) Analysis by reducing and non-reducing SDS-PAGE Coomassie.

References

1. D53 (TPD52L1) is a cell cycle-regulated protein maximally expressed at the G2-M transition in breast cancer cells.\n\nExp Cell Res 2005 Oct 15;310(1):152-65\n\n2. Alternative splicing as a mechanism for regulating 14-3-3 binding: interactions between hD53 (TPD52L1) and 14-3-3 proteins.\n\nJ Mol Biol 2003 Sep 19;332(3):675-87\n\n3. Identification and in situ hybridization mapping of a mouse Tpd52l1 (D53) orthologue to chromosome 10A4-B2.\n\nCytogenet Cell Genet 1998;81(3-4):199-201