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Tumor Type M2 Pyruvate Kinase, Recombinant, Human (M2PK, PKM2, Pyruvate kinase 3 isoform 1)

Cat no: P9545-31B

Tumor Type M2 Pyruvate Kinase, Recombinant, Human (M2PK, PKM2, Pyruvate kinase 3 isoform 1)

Recombinant human M2PK is expressed in E. coli with an amino-terminal hexahistidine tag.\n\nPyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence.\n\nEnzyme Activity: Not determined\n\nApplications: \nSuitable for use in ELISA. Other applications not tested.\n \nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

P9545-31B

Size

10ug

Applications

ELISA

Form

Supplied as a buffered liquid containing 50% glycerol.

Purity

Purified. (same/more than) 95% by SDS-PAGE.

References

Luftner D. et al. (2000) Anticancer Res. 20(6D): 5077-82.

Alternative Names

M2PK, PKM2, Pyruvate kinase 3 isoform 1

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