Tyk2 (8G8E) Antibody

Cat no: 252671

Supplier: ABBIOTEC

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Description
Additional Information

Tyk2 (Tyrosine kinase 2) is a 1187-amino acid protein (~131kDa), belongs to the family of non-receptor Janus tyrosine kinases, which also includes Jak1, Jak2, and Jak3. Kinases of the Jak family regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Tyk2 is activated by a variety of cytokines: IFN-alpha, IFN-beta, IL-6, IL-10, IL-12, and IL-13 and promotes IFN-gamma production by Th1-type CD4 cells. Tyk2 can be viewed as a dual-function Jak,Mouse,ediating both pro-inflammatory and anti-inflammatory cytokine responses. Tyk2 is also an important regulator of lymphoid tumor surveillance.

Catalogue number:	252671
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	P29597
Antigen:	Purified recombinant fragment of Tyk2 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	8G8E9?8G9H5,8G8B3
Additional info:	Non-receptor tyrosine-protein kinase TYK2; TYK2