Tyrosine Hydro, Xenopus/Amphibian,ylase Antibody

Cat no: 253234

Supplier: ABBIOTEC

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Description
Additional Information

Tyrosine hydro, Xenopus/Amphibian,ylase (TH) catalyzes the conversion of tyrosine to L-DOPA, which is the rate limiting step in the biosynthesis of catecholamines auch as dopamine, adrenalin and noradrenalin. Nerve cells with TH content are referred to as catecholaminergic cells and occurs mainly in the brain and adrenal glands. Defects in TH are the cause of Segawa syndrome, translating in progressive difficulty in walking. The activity of TH is also regulated by phosphorylation. Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs.

Catalogue number:	253234
Reactivities:	Human, Mouse
Applications:	Immunofluorescence, Immunohistochemistry
Size:	0.1 ml
Accession:	P04177
Antigen:	Native rat tyrosine hydro, Xenopus/Amphibian,ylase,Porcineurified from pheochromocytoma.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type:	Sheep Polyclonal Antibody
Isotype:	Sheep Ig
Additional info:	Tyrosine 3-hydro, Xenopus/Amphibian,ylase; Tyrosine 3-monoo, Xenopus/Amphibian,ygenase; TH; TYH