Tyrosine Hydro, Xenopus/Amphibian,ylase (Ser31) Antibody

Cat no: 252592

Supplier: ABBIOTEC

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Description
Additional Information

Tyrosine hydro, Xenopus/Amphibian,ylase (TH) catalyzes the conversion of tyrosine to L-DOPA, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. Nerve cells with TH content are referred to as catecholaminergic cells and occurs mainly in the brain and adrenal glands. Defects in TH are the cause of Segawa syndrome, translating in progressive difficulty in walking. The activity of TH is also regulated by phosphorylation. Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs.

Catalogue number:	252592
Reactivities:	Mouse, Rabbit
Applications:	Immunofluorescence, Immunohistochemistry
Size:	0.1 ml
Accession:	P04177
Antigen:	KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser31 of rat tyrosine hydro, Xenopus/Amphibian,ylase.
Format:	Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody
Isotype:	Rabbit IgG
Additional info:	Tyrosine 3-hydro, Xenopus/Amphibian,ylase; Tyrosine 3-monoo, Xenopus/Amphibian,ygenase; TH; TYH