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Tyrosine Hydroxylase, Phosphorylated (Ser40) (TH, TYH, Tyrosine 3 Hydroxylase, Tyrosine 3 Monooxygenase)

Tyrosine Hydroxylase, Phosphorylated (Ser40) (TH, TYH, Tyrosine 3 Hydroxylase, Tyrosine 3 Monooxygenase)

Cat no: T9237-10Q

Supplier: United States Biological
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Tyrosine hydroxylase in involved in the conversion of phenylalanine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines and as such has a key role in the physiology of adrenergic neurons. TH is encoded by four distinct mRNAs produced by alternative splicing of a single primary transcript. Expression of the mRNAs varies in different parts of the nervous system. Defects in TH are the cause of autosomal recessive Segawa syndrome. Applications: Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:1000 Western Blot: 1:1000 Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Immunohistochemistry (Frozen): 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T9237-10Q
Reactivities: Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 50ul
Form: Supplied as a liquid in 10mM HEPES, pH7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes the ~60kD tyrosine hydroxylase protein phosphorylated at Ser40. Species sequence homology: Mammalian

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