TZFP (Testis Zinc Finger Protein, FANCC-interacting Protein, Fanconi Anemia Zinc Finger Protein, FAXF, FAZF, Rog, Zinc Finger and BTB Domain Containing 32, ZBTB32, ZBTB32 Protein, ZNF538)

TZFP is a novel human PLZF-related transcription factor which is predominantly expressed in testis. The human TZFP contains a conserved N-terminal BTB (bric-a-brac, tramtrack, broad complex) or POZ (poxvirus, zinc finger) domain and three C-terminal PLZF-like C2H2 zinc fingers. A computer search of the protein data base revealed that the zinc finger domain of TZFP is more closely related to the promyelocytic leukemia zinc finger (PLZF) protein, which was previously reported to be a DNA-binding transcriptional repressor. The biological function and the target genes regulated by TZFP remain largely unknown.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

T9950-50

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

Hoatlin ME, Zhi Y, Ball H, Silvey K, Melnick A, Stone S, Arai S, Hawe N, Owen G, Zelent A, Licht JD. \nA novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF.\nBlood. 1999 Dec 1;94(11):3737-47.\nPMID: 10572087

Additional Info

Recognizes human TZFP.