Home  >  Products  >  TZFP (Testis Zinc Finger Protein, FANCC-interacting Protein, Fanconi Anemia Zinc Finger Protein, FAXF, FAZF, Rog, Zinc Finger and BTB Domain Containing 32, ZBTB32, ZBTB32 Protein, ZNF538)
TZFP (Testis Zinc Finger Protein, FANCC-interacting Protein, Fanconi Anemia Zinc Finger Protein, FAXF, FAZF, Rog, Zinc Finger and BTB Domain Containing 32, ZBTB32, ZBTB32 Protein, ZNF538)

TZFP (Testis Zinc Finger Protein, FANCC-interacting Protein, Fanconi Anemia Zinc Finger Protein, FAXF, FAZF, Rog, Zinc Finger and BTB Domain Containing 32, ZBTB32, ZBTB32 Protein, ZNF538)

Cat no: T9950-50

Supplier: United States Biological
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TZFP is a novel human PLZF-related transcription factor which is predominantly expressed in testis. The human TZFP contains a conserved N-terminal BTB (bric-a-brac, tramtrack, broad complex) or POZ (poxvirus, zinc finger) domain and three C-terminal PLZF-like C2H2 zinc fingers. A computer search of the protein data base revealed that the zinc finger domain of TZFP is more closely related to the promyelocytic leukemia zinc finger (PLZF) protein, which was previously reported to be a DNA-binding transcriptional repressor. The biological function and the target genes regulated by TZFP remain largely unknown. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: T9950-50
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: Hoatlin ME, Zhi Y, Ball H, Silvey K, Melnick A, Stone S, Arai S, Hawe N, Owen G, Zelent A, Licht JD. A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF. Blood. 1999 Dec 1;94(11):3737-47. PMID: 10572087
Additional info: Recognizes human TZFP.

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