UBE1L (5B10) Antibody

Cat no: 253054

Supplier: ABBIOTEC

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Description
Additional Information

UBE1L (Ubiquitin-activating enzyme E1 homolog UBE1L) a member of the E1 ubiquitin-activating enzyme family. Modification of proteins with ubiquitin is an important cellular mechanism for targeting. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases or E3s. UBE1L is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. UBE1L is e, Xenopus/Amphibian,pressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines abnormal or short-lived proteins for degradation.

Catalogue number:	253054
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	P41226
Antigen:	Purified recombinant fragment of human UBE1L e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	5B10
Additional info:	Ubiquitin-like modifier-activating enzyme 7; Ubiquitin-activating enzyme 7; D8; Ubiquitin-activating enzyme E1 homolog UBE1L; UBE2; UBA7