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Ubiquitin

Ubiquitin

Cat no: U1000-04E

Supplier: United States Biological
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Ubiquitin (Ub) is a small protein that is composed of 76aa. Ub is found only in eukaryotic organisms and is highly conserved. Ub can exist either in free form or as part of a complex with other proteins. In the latter case, Ub is attached (conjugated) to proteins through a covalent bond between the glycine at the C-terminal end of Ub and the side chains of lysine on the proteins; Ubiquitination. Ub functions to regulate protein turnover in a cell by closely regulating the degradation of specific proteins. Ubiquitin has been immunohistochemically localized to a number of pathological inclusions, including ; Lewy bodies of Parkinson
Catalogue number: U1000-04E
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid.
P type: Mab
Isotype: IgG1,k
Purity: Ascites
References: 1. Ross CA, et al. (2004) Trends Cell Biol. 14 (12) :703-11, 2. Hattori N, et al.(2004) Lancet. 364(9435):722-4.
Additional info: Recognizes human Ubiquitin.

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