UCHL1 Antibody

Cat no: 253236

Supplier: ABBIOTEC

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Description
Additional Information

Ubiquitin C-terminal hydrolase 1 (UCHL1) cleaves ubiquitin from other molecules. Genetic knockout of UCHL1 in mice results in a motor neuron degeneration similar to the spontaneous gracile a, Xenopus/Amphibian,onal dystrophy (gad) mutant mice. Point mutations in the UCHL1 gene are associated with some forms of human Parkinson's disease. Since UCHL1 is heavily e, Xenopus/Amphibian,pressed in neurons, it is released in large amounts following injury or degeneration. The detection of UCHL1 in CSF and other bodily fluids can be used as a biomarker.

Catalogue number:	253236
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunofluorescence
Size:	0.1 ml
Accession:	P09936
Antigen:	Recombinant full length human UCHL1 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml IgY in PBS pH7.4 with 0.065% sodium azide. Antibody was purified by PEG precipitation.
P type:	Chicken Polyclonal Antibody
Isotype:	Chicken Ig
Additional info:	Ubiquitin carbo, Xenopus/Amphibian,yl-terminal hydrolase isozyme L1; UCH-L1; Neuron cytoplasmic protein 9.5 PGP 9.5; PGP9.5; Ubiquitin thioesterase L1; UCHL1