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Ugt2b (UDP Glycosyltransferase 2 Family Polypeptide B)

Cat no: U0825-42

Ugt2b (UDP Glycosyltransferase 2 Family Polypeptide B)

The UDP-glucuronosyltransferases (UGTs, EC 2.4.1.17) comprise a large family of proteins capable of detoxifying a wide variety of both endogenous and exogenous substrates. The primary function of this gene superfamily is to catalyze the glycosylation of substrates such as biogenic amines, steroids, bile acids, phenolic compounds and various other pharmacologically relevant compounds, including numerous carcinogens, toxic environmental pollutants and prescription drugs. This conjugation increases the solubility of these compounds, allowing them to be excreted more readily through hepatic or renal mechanisms\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:32,000\nWestern Blot: 0.1-0.3ug/ml, observed in rat kidney lysates on ~50kD bands\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

U0825-42

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Rat

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

References

General References:\nPharmacogenetics. 2000 Apr;10(3):251-60.\nGenomic organization of the UGT2b gene cluster on human chromosome 4q13

Additional Info

Recognizes rat Ugt2b.

Read more on Supplier website

Applications

FC

Hosts

Mouse

Reactivities

Hum

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Applications

FC

Hosts

Mouse

Reactivities

Hum

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Applications

FC

Hosts

Mouse

Reactivities

Hum

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Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info
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