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UK-356618

Cat no: 022640


Supplier: United States Biological
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Potent and selective inhibitor of matrix metalloprotease-3 (MMP-3) (IC50 = 5.9 nM). Displays selectivity over a range of MMPs (IC50 values are 73, 840, 1790, 1900 and 51000 for MMP-13, MMP-9, MMP-2, MMP-14 and MMP-1 respectively). Form: Beige Solid Melting Point: 95-105 degrees C Solubility: Methanol Pfizer Compound
Catalogue number: 022640
Size: 10mg
Form: Beige Solid
Alternative names: (2R)-N1-[(1S)-2,2-Dimethyl-1-[[[(1R)-1-phenylethyl]amino]carbonyl]propyl]-N4-hydroxy-2-[3-(2-methyl[1,1'-biphenyl]-4-yl)propyl]butanediamide; UK 356618; PF-03890101;
References: Fray, M.J. et al.: Bioorg. Med. Chem. Lett., 11, 571 (2001); Fray, M.J. et al.: J. Med. Chem., 46, 3514 (2003);

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