UNC5B is a receptor for the netrin family of guidance molecules. It was identified as a mediator of the repulsive response in neurons and it is the only known netrin receptor with prominent endothelial expression. It has an important role in angiogenesis signaling.
Sequence:
The extracellular region of human UNC5B (aa 28-363) is fused at the C-terminus to the Fc portion of human IgG1.
Storage and Stability:
Short-term Storage: +4 degrees C
Long-term Storage: -20 degrees C
Stable for at least 6 months after receipt when stored at -20 degrees C.