Home  >  Products  >  uPA (Urokinase-type Plasminogen Activator, U-plasminogen Activator, PLAU)
uPA (Urokinase-type Plasminogen Activator, U-plasminogen Activator, PLAU)

uPA (Urokinase-type Plasminogen Activator, U-plasminogen Activator, PLAU)

Cat no: U2599-07P

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Urokinase is a potent 50kD serine protease which is also known as urokinase plasminogen activator (uPA). uPA cleaves and activates plasminogen to form plasmin and is involved in extracellular cellular matrix degradation and cell signalling. Recent studies have implicated uPA and its receptor in the pathogenesis of inflammation and immunity. A specific polymorphism in the gene encoding uPA may be associated with late-onset Alzheimer's disease. The levels of uPA, uPAR and its soluble fragments have also been found to be increased in tissues, plasma and other body fluids of cancer patients and to be markers of cancer development and metastasis. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: U2599-07P
Reactivities: Human
Hosts: Rabbit
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
References: 1. Huai,Q., Mazar,A.P., Kuo,A., Parry,G.C., Shaw,D.E., Callahan,J., Li,Y., Yuan,C., Bian,C., Chen,L., Furie,B., Furie,B.C., Cines,D.B. and Huang,M. Structure of human urokinase plasminogen activator in complex with its receptor. Science 311 (5761), 656-659 (2006).
Additional info: Recognizes human PLAU. Species Crossreactivity: orangutan. Species sequence homology: mouse and rat.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave