Home  >  Products  >  Urea Transporter A1 (Slc14a2. Solute carrier family 14 (urea transporter), member 2, Slc14a2T, Solute carrier family 14 member 2, Urea transporter, kidney, Urea transporter 2, UrT1-C, UrT1-D, Ut2)
Urea Transporter A1 (Slc14a2. Solute carrier family 14 (urea transporter), member 2, Slc14a2T, Solute carrier family 14 member 2, Urea transporter, kidney, Urea transporter 2, UrT1-C, UrT1-D, Ut2)

Urea Transporter A1 (Slc14a2. Solute carrier family 14 (urea transporter), member 2, Slc14a2T, Solute carrier family 14 member 2, Urea transporter, kidney, Urea transporter 2, UrT1-C, UrT1-D, Ut2)

Cat no: U2013-10A

Supplier: United States Biological
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UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates transepithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promotor and expressed in the thin descending limb of Henle, viz. UT-A2.) (1, 2). Applications: Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: U2013-10A
Reactivities: Mouse, Rat
Hosts: Rabbit
Applications: Immunocytochemistry, Western Blot
Size: 100ul
Form: Supplied as a liquid in 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Serum
References: 1. Nielsen S, Terris J, Smith CP, Hediger MA, Ecelbarger CA, Knepper MA. (1996) Proc Natl Acad Sci U S A. 93(11):5495-500. 2. Smith C.P. (2009) Exp Physiol. 94(2): 180-185.
Additional info: Recognizes rat UT-A1. Species Crossreactivity: mouse.

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