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Urodilatin (Atrial Natriuretic Peptide)

Cat no: U1750-01


Supplier: United States Biological
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Urodilatin is a natriuretic peptide isolated from human urine and belongs to the family of A type natriuretic peptides. Urodilatin is differentially processed to a peptide of 32aa from the same precursor as ANP. It is synthesized in kidney tubular cells and secreted luminally. After secretion from epithelial cells of the distal and/or connecting tubules, Urodilatin interacts downstream at distal segments of the nephron with luminally located receptors whereby it regulates Na(+) and water reabsorption. Thus, the physiological function of the renal Urodilatin system can be described as a paracrine intrarenal regulator for Na(+) and water homeostasis, considering Urodilatin as a real diuretic natriuretic regulatory peptide. Applications: Suitable for use in ELISA, RIA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4 degrees C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: U1750-01
Hosts: Rabbit
Size: 20ul
Form: Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute in ddH2O.
P type: Pab
Purity: Serum
Additional info: Recognizes synthetic human Urodilatin. There were no cross reactivities obtained with human ANP (aa 1-28) (< 0,1%); human pro-ANP (aa 1-98) (< 0,1%); human pro-ANP (aa 79-98) (< 0,1%); human BNP (< 0,1%); and human CNP (< 0,1%).

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