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Uroguanylin (aa1-8) (UGN, Guanylate Cyclase Activator 2B, GUCA2B)

Uroguanylin (aa1-8) (UGN, Guanylate Cyclase Activator 2B, GUCA2B)

Cat no: U2585-01C

Supplier: United States Biological
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Uroguanylin is a 16aa peptide that is secreted by enterochromaffin cells in the duodenum and proximal small intestine. Guanylin acts as an agonist of the guanylyl cyclase receptor GC-C and regulates electrolyte and water transport in intestinal and renal epithelia. Applications: Suitable for use in ELISA, Immunohistochemistry, Western Blot and RIA. Other applications not tested. Recommended Dilutions: ELISA: 1:2000 Immunohistochemistry (Acrylic resin): 1:800 Western Blot: 1:1000 RIA: 1:10,000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: U2585-01C
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 20ul
Form: Supplied as a lyophilized powder. Reconstitute with 20ul sterile ddH2O.
P type: Pab
Isotype: IgG
Purity: Serum
References: 1.Hess, R., et al., (1995), "GCAP-II: isolation and characterization of the circulating form of human uroguanylin", FEBS Lett., 374(1): 34-38 2.M
Additional info: Recognizes human Uroguanylin aa1-8 (FKTLRTIA) circulating form.

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