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Urokinase, CT (Urokinase-type Plasminogen Activator, U-plasminogen Activator, uPA, PLAU)

Urokinase, CT (Urokinase-type Plasminogen Activator, U-plasminogen Activator, uPA, PLAU)

Cat no: U2599-07N

Supplier: United States Biological
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Urokinase is a potent 50kD serine protease which is also known as urokinase plasminogen activator (uPA). uPA cleaves and activates plasminogen to form plasmin and is involved in extracellular cellular matrix degradation and cell signalling. Recent studies have implicated uPA and its receptor in the pathogenesis of inflammation and immunity. A specific polymorphism in the gene encoding uPA may be associated with late-onset Alzheimer
Catalogue number: U2599-07N
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-saline, pH 7.3, 0.02% sodium azide, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Mondino, A. & Blasi, F. (2004) uPA and uPAR in fibrinolysis, immunity and pathology. Trends Immunol. 25: 450-455. 2. Dano, K. et al. (2005) Plasminogen activation and cancer. Thromb Haemost. 93: 676-681.
Additional info: Recognizes an epitope within the C-terminal of human urokinase.

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