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Vandetanib

Cat no: 022723


Supplier: United States Biological
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Vandetanib is a once-daily oral inhibitor of vascular endothelial growth factor receptor-2 and epidermal growth factor receptor kinase activity. The activity of Vandetanib plus Docetaxel was assessed in patients with previously treated non-small-cell lung cancer (NSCLC). Form: Off-White to Pale Yellow Solid Melting Point: 240-243 degrees C Solubility: Methanol
Catalogue number: 022723
Size: 5mg
Form: Off-White to Pale Yellow Solid
Alternative names: N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy- 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline; ZD 6474; Zactima;
References: Bruns, C., et al.: Clin. Cancer Res., 6, 1936 (2000), Hennequin, L., et al.: J. Med. Chem., 45, 1300 (2002), Park, M., et al.: J. Biol. Chem., 278, 50624 (2003), Arao, T., et al.: Cancer Res., 64, 9101 (2004), Prueitt, R., et al.: Int. J. Cancer, 120, 796 (2007),

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