Home  >  Products  >  VAP-1 (Vascular Adhesion Protein 1, VAP1, Amine Oxidase Copper-containing 3 (Vascular Adhesion Protein 1), AOC3, Copper Amine Oxidase, HPAO, Membrane Copper Amine Oxidase, Semicarbazide-sensitive Amine Oxidase, SSAO, VP97)
VAP-1 (Vascular Adhesion Protein 1, VAP1, Amine Oxidase Copper-containing 3 (Vascular Adhesion Protein 1), AOC3, Copper Amine Oxidase, HPAO, Membrane Copper Amine Oxidase, Semicarbazide-sensitive Amine Oxidase, SSAO, VP97)

VAP-1 (Vascular Adhesion Protein 1, VAP1, Amine Oxidase Copper-containing 3 (Vascular Adhesion Protein 1), AOC3, Copper Amine Oxidase, HPAO, Membrane Copper Amine Oxidase, Semicarbazide-sensitive Amine Oxidase, SSAO, VP97)

Cat no: V2095-02D

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
VAP-1 is present in endothelial cells, smooth muscle cells, adipocytes, and in follicular dendritic cells. The majority of VAP-1 is stored within intracellular granules and translocated to the endothelial surface on inflammation. Structurally it belongs to enzymes called semicarbamizide-sensitive amine oxidases. These enzymes deaminate primary amines in a reaction producing hydrogen peroxide, aldehyde, and ammonia. VAP-1 possesses both adhesive and enzymatic properties in vitro. VAP-1 mediates leukocyte trafficking to sites of inflammation. The monoclonal antibody 174-5 cross-reacts with rat VAP-1. Applications: Suitable for use in Flow Cytometry, Immunofluorescence, Western Blot and Immunohistochemistry on frozen sections. Useful for inhibition of biological activity. Inhibits lymphocyte infiltration in liver allograft rejection in rats. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: V2095-02D
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.1% BSA.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
References: 1. Martelius, T et al; Blockade of vascular adhesion protein-1 inhibits lymphocyte infiltration in rat liver allograft rejection. Am J Path 2004, 165: 1993.
Additional info: Recognizes human Vascular Adhesion Protein-1 (VAP-1) also known as AOC3, a heavily sialylated homodimeric glycoprotein of 180 kD.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave