Vascular Endothelial Growth Factor Receptor 1 (VEGF Receptor 1, VEGFR 1, VEGFR1, VEGFR-1, EC 2.7.10.1, FLT, Fms-like Tyrosine Kinase 1, Flt 1, Flt1, Flt-1, Fms Related Tyrosine Kinase 1, Fms-related Tyrosine Kinase 1 (Vascular Endothelial Growth Factor/Va

VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity. Because sFLT1 has a higher affinity for VEGF than does FLK1, it may function as an inhibitor of VEGF response.\n\nApplications: \nSuitable for use in ELISA, Flow Cytometry and Immunocytochemistry. Other applications not tested.\n\nRecommended Dilutions:\nFlow Cytometry: Detects Flt-1 positive cells (e.g.PAE/Flt-1 cells)\nImmunocytochemistry (IF): 5-30ug/ml\nELISA: 1.5-8ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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