VCX3A, NT (VCX3A, VCX3, VCX8R, VCXA, Variable charge X-linked protein 3, Variable charge protein on X with eight repeats, Variably charged protein X-A) (AP)

This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq].\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

043732-AP

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Alkaline Phosphatase.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Jiao, X., et al. J. Neurosci. 29(40):12419-12427(2009)\nCuevas-Covarrubias, S.A., et al. Br. J. Dermatol. 158(3):483-486(2008)\nJiao, X., et al. Mol. Cell 24(5):713-722(2006)\nFukami, M., et al. Am. J. Hum. Genet. 67(3):563-573(2000)\nLahn, B.T., et al. Hum. Mol. Genet. 9(2):311-319(2000)

Additional Info

Human

Alternative Names

VCX3A, VCX3, VCX8R, VCXA, Variable charge X-linked protein 3, Variable charge protein on X with eight repeats, Variably charged protein X-A