VDAC-1 Antibody

Cat no: 251931

Supplier: ABBIOTEC

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Description
Additional Information

Voltage-dependent anion-selective channel protein 1 (VDAC-1) forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; whereas in the plasma membrane it is involved in cell volume regulation and apoptosis. VDAC-1 adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has weak anion selectivity whereas the closed state is cation-selective. VDAC-1 participates in the formation of the permeability transition pore comple, Xenopus/Amphibian, (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.

Catalogue number:	251931
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	P21796
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human VDAC-1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Voltage-dependent anion-selective channel protein 1; VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; VDAC1; VDAC