Home  >  Products  >  VDAC2 (Voltage Dependent Anion Channel 2, Voltage-dependent Anion-selective Channel Protein 2, VDAC-2, hVDAC2, FLJ23841, Outer Mitochondrial Membrane Protein Porin 2, POR)
VDAC2 (Voltage Dependent Anion Channel 2, Voltage-dependent Anion-selective Channel Protein 2, VDAC-2, hVDAC2, FLJ23841, Outer Mitochondrial Membrane Protein Porin 2, POR)

VDAC2 (Voltage Dependent Anion Channel 2, Voltage-dependent Anion-selective Channel Protein 2, VDAC-2, hVDAC2, FLJ23841, Outer Mitochondrial Membrane Protein Porin 2, POR)

Cat no: V2121-21C

Supplier: United States Biological
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VDAC2 (voltage-dependent anion-selective channel protein 2), a mammalian mitochondrial outer-membrane protein, and member of the eukaryotic mitochondrial porin family, which allows for the passage/diffusion of small hydrophilic molecules. VDAC2 interacts with hexokinases, and has been shown to interact specifically with the inactive conformer of the proapoptotic protein BAK, thereby providing a link between mitochondrial physiology and the core apoptotic pathway. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.3-1ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Heart lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V2121-21C
Reactivities: Human
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Chandra D, Choy G, Daniel PT, Tang DG. Bax-dependent regulation of Bak by voltage-dependent anion channel 2. J Biol Chem. 2005 May 13;280(19):19051-61. Epub 2005 Mar 9. PMID: 15757910
Additional info: Recognizes human VDAC2. Species sequence homology: canine, mouse, rat.

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