VDAC2 (voltage-dependent anion-selective channel protein 2), a mammalian mitochondrial outer-membrane protein, and member of the eukaryotic mitochondrial porin family, which allows for the passage/diffusion of small hydrophilic molecules. VDAC2 interacts with hexokinases, and has been shown to interact specifically with the inactive conformer of the proapoptotic protein BAK, thereby providing a link between mitochondrial physiology and the core apoptotic pathway.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution:
Western Blot: 0.3-1ug/ml
Optimal dilutions to be determined by the researcher.
Positive Control:
Human Heart lysate
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.