Home  >  Products  >  VDAC2 (Voltage Dependent Anion Channel 2, Voltage-dependent Anion-selective Channel Protein 2, VDAC-2, hVDAC2, FLJ23841, Outer Mitochondrial Membrane Protein Porin 2, POR)
VDAC2 (Voltage Dependent Anion Channel 2, Voltage-dependent Anion-selective Channel Protein 2, VDAC-2, hVDAC2, FLJ23841, Outer Mitochondrial Membrane Protein Porin 2, POR)

VDAC2 (Voltage Dependent Anion Channel 2, Voltage-dependent Anion-selective Channel Protein 2, VDAC-2, hVDAC2, FLJ23841, Outer Mitochondrial Membrane Protein Porin 2, POR)

Cat no: V2121-21D

Supplier: United States Biological
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VDAC2 (voltage-dependent anion-selective channel protein 2), a mammalian mitochondrial outer-membrane protein, and member of the eukaryotic mitochondrial porin family, which allows for the passage/diffusion of small hydrophilic molecules. VDAC2 interacts with hexokinases, and has been shown to interact specifically with the inactive conformer of the proapoptotic protein BAK, thereby providing a link between mitochondrial physiology and the core apoptotic pathway. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml ELISA: >1:1000 Optimal dilutions to be determined by the researcher. Positive Control: Human brain Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V2121-21D
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Blachly-Dyson E, Zambronicz EB, Yu WH, Adams V, McCabe ER, Adelman J, Colombini M, Forte M. Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel. J Biol Chem. 1993 Jan 25;268(3):1835-41. PMID: 8420959
Additional info: Recognizes human VDAC2.

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