An antidiabetic agent. A potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that breaks down Glucagon-like peptide 1 (GLP-1). By delaying the degradation of GLP-1, vildagliptin extends the action of insulin while also suppressing the release of glucagon. This leads to a reduction in elevated blood glucose levels (hyperglycemia), which is a characteristic feature of type 2 diabetes.
Solubility:
DMSO, H2O
Molecular Weight:
~303.4
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Quick Search
Products ![Vildagliptin ((S)-1-[N-(3-hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrile)](/system/suppliers/default_product_images/000/000/160/main/US-Biological-Life-Sciences.jpg?1386100414)
