Vinculin Antibody

Cat no: 251810

Supplier: ABBIOTEC

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Description
Additional Information

In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matri, Xenopus/Amphibian, junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in inculin are the cause of cardiomyopathy dilated type 1W (CMD1W). Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Catalogue number:	251810
Reactivities:	Human, Mouse, Chicken/Bird, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P18206
Antigen:	Human vinculin,Porcineurified from uterus.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	VIN-54
Additional info:	Vinculin; Metavinculin; VCL