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Vitamin D Binding Protein (VCBP/GC (aa18-30)(Group-specific Component)

Cat no: V2130-21B


Supplier: United States Biological
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The vitamin D binding protein (DBP) is a multifunctional plasma protein that can modulate certain immune and inflammatory responses. The diverse cellular functions of DBP appear to require cell surface binding to mediate these processes. Numerous reports have detected DBP bound to the surface of several cell types and would support the concept of a cell surface binding site for DBP. Applications: Suitable for use in Peptide ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Peptide ELISA: 1:1000 Western Blot: 0.5-3ug/ml detects ~60kD observed human Lung and Ovary lysates (calculated MW of 52.9kD according to NP_000574.2) Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V2130-21B
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: vitamin D-binding protein/group specific component, vitamin D-binding protein, vitamin D-binding alpha-globulin, vitamin D binding protein, VDBP, VDBG, DBP/GC, DBP, group-specific component (vitamin D binding protein), GC
References: 1. Sandford AJ, Pare PD. Genetic risk factors for chronic obstructive pulmonary disease. Clin Chest Med. 2000 Dec;21(4):633-43. Review.
Additional info: Recognizes human Vitamin D Binding Protein. Species Sequence Homology: mouse, rat and canine

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