Home  >  Products  >  Vitamin D Binding Protein (VDBP, VDB, DBP, DBP/GC, Gc Globulin, Group Specific Component, Group-specific Component, GC, hDBP, Vitamin D Binding alpha Globulin, VDBG)
Vitamin D Binding Protein (VDBP, VDB, DBP, DBP/GC, Gc Globulin, Group Specific Component, Group-specific Component, GC, hDBP, Vitamin D Binding alpha Globulin, VDBG)

Vitamin D Binding Protein (VDBP, VDB, DBP, DBP/GC, Gc Globulin, Group Specific Component, Group-specific Component, GC, hDBP, Vitamin D Binding alpha Globulin, VDBG)

Cat no: V2130-10C

Supplier: United States Biological
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Vitamin D binding protein (VDBP) is the major carrier protein of vitamin D that also transports components such as fatty acids and endotoxins and has an important role in the actin scaveging system. VDBP is a 52-58kD plasma protein synthesized mainly by hepatocytes. Polymorphisms in the gene give rise to three major electrophoretic variants, Gc1, Gc1s and Gc1f that differ by amino acid substitutions as well as glycosylations. The physiological significance of these phenotypes has yet to be determined. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: I1904-40A: IgG, H&L, X-Adsorbed (HRP) Pab Gt xRb I1904-46Q: IgG, H&L (HRP) Pab Gt xRb I1904-40J: IgG, Fc (HRP) Pab Gt xRb I1904-40M: IgG, Fc, X-Adsorbed (FITC) Pab Gt xRb I1904-40H: IgG, Fc (Biotin) Pab GtxRb Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V2130-10C
Reactivities: Human
Hosts: Rabbit
Applications: ELISA
Size: 1ml
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
References: 1. Ho, A.S. et al (2010) Novel biomarkers predict liver fibrosis in hepatitis C patients: alpha 2 macroglobulin, vitamin D binding protein and apolipoprotein AI. J Biomed Sci. 17: 58.
Additional info: Recognizes human VDBP.

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