Von Willebrand Factor Antibody

Cat no: 251228

Supplier: ABBIOTEC

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Description
Additional Information

Von Willebrand Factor (VWF) plays a role in the maintenance of hemostasis, where it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matri, Xenopus/Amphibian, and platelet-surface receptor comple, Xenopus/Amphibian, GPIb-I, Xenopus/Amphibian,-V. It also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. Defects in VWF are the cause of von Willebrand disease (VWD), a group of hemorrhagic disorders in which the von Willebrand factor is either quantitatively or qualitatively abnormal, resulting in altered platelet function. Symptoms vary depending on severity and disease type but may include prolonged bleeding time, deficiency of factor VIII and impaired platelet adhesion.

Catalogue number:	251228
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P04275
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Von Willebrand Factor.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Vwf; vWF; von Willebrand factor; F8VWF; von Willebrand antigen 2; von Willebrand antigen II; VWF