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Von Willebrand Factor (vWF, Factor VIII Related Antigen)

Cat no: V2700-01G

Von Willebrand Factor (vWF, Factor VIII Related Antigen)

Von Willebrand factor (vWf) is a series of self-aggregated structures, all derived from common glycoprotein subunits, synthesized in endothelial cells and megakaryocytes. The molecular mass of the monomeric vWf unit is 225kD. vWf binds to circulating factor VIIIc (antihemophilic factor), hereby stabilizing the latter thus beeing an important factor in the normal primary haemostasis.\n\nApplications:\nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilutions:\nOptimal dilutions to be determined by the researcher.\n\nHybridoma: \nX63-Ag8.653 myeloma cells with spleen cells from female CF1 x BALB/c mice.\n\nCulture Medium:\nDulbecco

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SPECIFICATIONS

Catalog Number

V2700-01G

Size

100ul

Applications

ELISA

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide

P Type

Mab

Purity

Purified by Protein A/G affinity chromatography

Isotype

IgG1,k

References

1. Scott T & Eagleson M (1988) Concise Encyclopedia Biochemistry: Walter de Gruyter, New York.

Additional Info

Recognizes human vWf from serum or plasma. Reacts strongly with vWf in ELISA with vWf directly coated onto the microtiterplate, and also when used in sandwich ELISA in combination with a polyclonal antibody against the antigen. Epitope specificity differs from that of V2700-01F.

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